Cross-Linking (Corneal Cross-Linking Treatment)

Cross-Linking is an effective treatment used in keratoconus and corneal ectasia. In keratoconus, the cornea thins and collagen fibers weaken. Cross-Linking strengthens these fibers to stop disease progression. The goal is not to eliminate refractive error but to stabilize the cornea. Patients should avoid makeup, perfume, and creams before the procedure and must attend with a companion.

What is Corneal Cross-Linking? What are the Procedure Steps?

The epithelial layer is removed. Riboflavin (vitamin B2) drops are applied for 20–30 minutes. After adequate absorption, ultraviolet A (UVA) light is applied for 8–10 minutes. The interaction strengthens collagen fibers and stiffens the cornea.

Post-Procedure and Healing Process

A protective contact lens is placed. Burning, tearing, and discomfort may occur for 4–5 days. After epithelial healing, the lens is removed. Eye drops must be used as prescribed. Vision may remain blurred for several weeks.

Follow-Up and Monitoring After Cross-Linking

Regular follow-ups monitor disease stability. The procedure may be repeated if necessary. The aim is to strengthen and stabilize the cornea.

Indications for Cross-Linking

In addition to keratoconus, it can be used in post-laser corneal ectasia. Suitability is determined after detailed examination.